It's not 100% required, but we have found that some AVs can cause high CPU utilization when scanning some of the CU binaries.
If you want to whitelist the following it may be advantageous in preventing or resolving issues:
On End-Points with the CU Agent installed:
C:\Program Files\Smart-X\ControlUpAgent\Version X.X.X.X\AppLoadTimeTracer.exe
C:\Program Files\Smart-X\ControlUpAgent\Version X.X.X.X\cuAgent.exe
On the Monitor Server(s):
C:\Program Files\Smart-X\ControlUpMonitor\Version X.X.X.X\cuMonitor.exe
If you would like to validate that our binaries are safe, you can scan against them on https://www.virustotal.com
The report will show you the files are digitally signed properly and clean of any viral engines.